OVERVIEW:

SynonymsMonoclonalComplementC1qantibody,Anti-ComplementC1qantibody,C1qantibody,ComplementC1q,ComplementCq1,ComplementCq-1antibody,ComplementCq1antibody,ComplementCq-1
SpecificityHumancomplementC1q
CrossReactivityHuman
ApplicationsELISA,Inhibition,WB
ImmunogenComplementC1qantibodywasraisedinmouseusinghumancomplementC1qastheimmunogen.

SPECIFICATIONS:

HostMouse
Clone242G3
IsotypeIgG1
MethodofPurificationProteinAaffinitychromatography
Form&BufferLyophilized.Reconstitutein1mldist.water(finalsolutioncontains0.09%NaN3,0.5%BSAinPBSbuffer,pH7.4)

STORAGE&SAFETY:

StorageStoreat4degCuntilreconstitution.Followingreconstitutionaliquotandfreezeat-20degCforlongtermstorage.Avoidrepeatedfreeze-thawcycles.

UsageAssayInformation:

UsageRecommendationsWB:1:100

GENERALINFORMATION:

BIOLOGicalSignificanceTheC1qcomplexispotentiallymultivalentforattachmenttothecomplementfixationsitesofimmunoglobulin.ThesitesareontheCH2domainofIgGandprobablyontheCH4domainofIgM.Theappropriatepeptidesequenceofthecomplementfixingsitemightbecomeexposedfollowingcomplexingoftheimmunoglobulin,orthesitesmightalwaysbeavailable,butmightrequiremultipleattachmentbyC1qwithcriticalgeometryinordertoachievethenecessaryAvidity.